Mechanistic studies on the reduction of 2-bromo-1-phenylethylidenemalononitrile by NADH models BNAH and AcrH2

Authors

You Cheng Liu, State Key Laboratory of Applied Organic Chemistry
Bin Li, State Key Laboratory of Applied Organic Chemistry
Qing Xiang Guo, State Key Laboratory of Applied Organic Chemistry

Document Type

Article

Publication Date

11-7-1994

Abstract

Reduction of 2-bromo-1-phenylethylidenemalononitrile (BPM) by coenzyme NADH models BNAH and AcrH2 to give 2-phenyl-1, 1-cyclopropanedicarbonitrile (PCN) and 1-phenylethylidenemalononitrile (PM), respectively, was rationalized in terms of a direct hydride transfer with BNAH and an initial electron transfer with AcrH2. © 1994.

Publication Source (Journal or Book title)

Tetrahedron Letters

First Page

8429

Last Page

8432

Recommended Citation

Liu, Y., Li, B., & Guo, Q. (1994). Mechanistic studies on the reduction of 2-bromo-1-phenylethylidenemalononitrile by NADH models BNAH and AcrH2. Tetrahedron Letters, 35 (45), 8429-8432. https://doi.org/10.1016/S0040-4039(00)74425-X