Anesthesine modified polysacharides--I: Synthesis and characterization

Document Type

Conference Proceeding

Publication Date

12-1-1991

Abstract

A novel synthetic polycarboxylic compound, modified cellulose, is presented in which the p-aminobenzoic acid is linked via anesthesine (p-aminoethyl benzoate) to carboxylic groups of chlorite-oxidized cellulose, both as spacer and to increase the hydrophobicity of the polymer. The structure of the modified cellulose is characterized by thin-layer chromatography and by IR and NMR spectra. It is shown that the introducing of a spacer, i.e. the decrease of negative charge by placing the carboxylic group away from the main chain, affects the cytotoxic effect of the polymer.

Publication Source (Journal or Book title)

Proceedings of the Annual Conference on Engineering in Medicine and Biology

First Page

1492

Last Page

1493

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