Document Type
Patent
Patent Number
AU 2014214709B2
Abstract
The present invention relates to a device comprising a biomolecular processor. Each biomolecular processor has one or more bioreactor chambers defined by a solid substrate; a support structure within each bioreactor; a cleaving enzyme immobilized to the support structure and operatively positioned within the bioreactor chamber to cleave monomer or multimer units of a biopolymer molecule operatively engaged by the cleaving enzyme; and one or more time-of-flight channels formed in the solid substrate and fluidically coupled to said one or more bioreactor chambers. Each of the time-of-flight channels have two or more sensors including at least (i) a first sensor contacting the time-of-flight channel proximate to the input end of the channel and (ii) a second sensor contacting the time-of-flight channel proximate to the output end of channel. The present invention further relates to methods of sequencing and identifying biopolymer molecules using the device.
Application Number
AU2014214709A
Assignees
Louisiana State University
Publication Date
5-31-2018
Recommended Citation
Barany, F., Grills, G., McCarley, R., Mckinney, C., Moldovan, D., Murphy, M., Nikitopoulos, D., Park, S., Podlaha-Murphy, E., & Soper, S. (2018). Biomolecular Processing Platform and Uses Thereof. Retrieved from https://repository.lsu.edu/science_patents/31