Document Type
Patent
Patent Number
CA 2896674C
Abstract
The present invention relates to a device that includes a biomolecular processing unit. Each biomolecular processing unit has one or more bioreactor chambers defined by a solid substrate; a support structure in each bioreactor; a cleavage enzyme immobilized on the support structure and operably positioned in the bioreactor chamber to cleave monomer units or multimer units of a biopolymer molecule operably engaged by the cleavage enzyme; one or more time-of-flight channels formed in the solid substrate and fluidly coupled to said one or more bioreactor chambers. Each of the time-of-flight channels has at least two sensors comprising at least (i) a first sensor contacting the time-of-flight channel near the input end of the channel and (ii) a second sensor contacting the time-of-flight channel near the output end of the channel. The present invention further relates to methods of sequencing and identifying biopolymer molecules using the device.
Application Number
CA2896674A
Assignees
Louisiana State University
Publication Date
7-6-2021
Recommended Citation
Soper, S., Barany, F., Grills, G., McCarley, R., Mckinney, C., Moldovan, D., Murphy, M., Nikitopoulos, D., Park, S., & Podlaha-Murphy, E. (2021). Biomolecular Processing Platform and Uses Thereof. Retrieved from https://repository.lsu.edu/science_patents/13