Promoting Successful Weight Loss in Primary Care in Louisiana (PROPEL): Rationale, design and baseline characteristics

Authors

Peter T. Katzmarzyk, Pennington Biomedical Research Center, Baton Rouge, LA, United States. Electronic address: Peter.Katzmarzyk@pbrc.edu.
Corby K. Martin, Pennington Biomedical Research Center, Baton Rouge, LA, United States.
Robert L. Newton, Pennington Biomedical Research Center, Baton Rouge, LA, United States.
John W. Apolzan, Pennington Biomedical Research Center, Baton Rouge, LA, United States.
Connie L. Arnold, Department of Medicine, Feist-Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, LA, United States.
Terry C. Davis, Department of Medicine, Feist-Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, LA, United States.
Kara D. Denstel, Pennington Biomedical Research Center, Baton Rouge, LA, United States.
Emily F. Mire

Document Type

Article

Publication Date

4-1-2018

Abstract

UNLABELLED: Underserved and minority populations suffer from a disproportionately high prevalence of obesity and related comorbidities. Effective obesity treatment programs delivered in primary care that produce significant weight loss are currently lacking. The purpose of this trial is to test the effectiveness of a pragmatic, high intensity lifestyle-based obesity treatment program delivered within primary care among an underserved population. We hypothesize that, relative to patients who receive usual care, patients who receive a high-intensity, health literacy- and culturally-appropriate lifestyle intervention will have greater percent reductions in body weight over 24 months. Eighteen clinics (N = 803 patients) serving low income populations with a high proportion of African Americans in Louisiana were randomized to the intervention or usual car. Patients in the intervention participate in a high-intensity lifestyle program delivered by health coaches employed by an academic health center and embedded in the primary care clinics. The program consists of weekly (16 in-person/6 telephone) sessions in the first six months, followed by sessions held at least monthly for the remaining 18 months. Primary care practitioners in usual care receive information on weight management and the current Centers for Medicare and Medicaid Services reimbursement for obesity treatment. The primary outcome is percent weight loss at 24 months. Secondary outcomes include absolute 24-month changes in body weight, waist circumference, blood pressure, fasting glucose and lipids, health-related quality of life, and weight-related quality of life. The results will provide evidence on the effectiveness of implementing high-intensity lifestyle and obesity counseling in primary care settings among underserved populations. TRIAL REGISTRATION: ClinicalTrials.gov Identifier NCT02561221.

Publication Source (Journal or Book title)

Contemporary clinical trials

First Page

1

Last Page

10

Recommended Citation

Katzmarzyk, P. T., Martin, C. K., Newton, R. L., Apolzan, J. W., Arnold, C. L., Davis, T. C., Denstel, K. D., & Mire, E. F. (2018). Promoting Successful Weight Loss in Primary Care in Louisiana (PROPEL): Rationale, design and baseline characteristics. Contemporary clinical trials, 67, 1-10. https://doi.org/10.1016/j.cct.2018.02.002