Document Type
Article
Publication Date
1-1-2002
Abstract
We determined whether an antifungal 14-kDa protein trypsin inhibitor isolated from corn is able to cross the blood-brain barrier. We found that it completely crossed the blood-brain barrier by means of a saturable mechanism at a rate of 0.153 μl/g · min, with about 0.082% of the intravenously injected dose being taken up per gram of brain.
Publication Source (Journal or Book title)
Antimicrobial Agents and Chemotherapy
First Page
2633
Last Page
2635
Recommended Citation
Banks, W., Niehoff, M., Brown, R., Chen, Z., & Cleveland, T. (2002). Transport of an antifungal trypsin inhibitor isolated from corn across the blood-brain barrier. Antimicrobial Agents and Chemotherapy, 46 (8), 2633-2635. https://doi.org/10.1128/AAC.46.8.2633-2635.2002
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