Survey of Immunoglobulin G Content and Antibody Specificity in Cows’ Milk from British Columbia
Document Type
Article
Publication Date
1-1-1994
Abstract
The immunoglobulin G (IgG) concentrations of 254 raw milk samples collected from the province of British Columbia (Canada) in 1990 and 1991 ranged from 0.030 to 0.71 mg ml-1, with mean and median values of 0.28 and 0.27 mg ml-1 respectively in 1990, and 0–25 and 0.24 mg ml-1 respectively in 1991. Although significant differences were noted in IgG contents of milks from five geographical areas and 14 dairies for each of the 2 years, there were also significant differences between milks from year to year. All of the milks showed measurable antigen-binding activity in enzyme-linked immunosorbent assay (ELISA) against the lipopolysaccharide (LPS) fractions of five bacteria (Shigella flexneri 1A, Escherichia coli O111:B4, Escherichia coli 0128:B12, Salmonella typhimurium and Salmonella enteritidis). An immune milk obtained from vaccinated cows showed significantly higher anti-S. enteritidis LPS activity than any of the raw milk samples. However, levels of specific anti-LPS activity against the other four bacteria were roughly of the same order of magnitude for raw milk samples and the immune milk. © 1994, Taylor & Francis Group, LLC. All rights reserved.
Publication Source (Journal or Book title)
Food and Agricultural Immunology
First Page
443
Last Page
451
Recommended Citation
Li-Chan, E., Kummer, A., Losso, J., & Nakai, S. (1994). Survey of Immunoglobulin G Content and Antibody Specificity in Cows’ Milk from British Columbia. Food and Agricultural Immunology, 6 (4), 443-451. https://doi.org/10.1080/09540109409354856