Heat and mass transfer models and measurements for low-temperature storage of biological systems

Document Type

Article

Publication Date

7-5-2018

Abstract

Living systems are routinely exposed to low temperatures, and their corresponding response has been of scientific and medical interest for centuries. The basic physicochemical phenomena that govern the response of the living systems to subzero temperatures are complex and interactively coupled so that the prediction and regulation of the associated events are often difficult. However, during the past several decades, significant progress has been made in devising useful techniques to further our understanding of biological systems at ultralow temperatures. This chapter presents some of the heat and mass transfer models and associated measurements in biological systems exposed to low temperatures specifically as applied to cryopreservation protocols.

Publication Source (Journal or Book title)

Handbook of Thermal Science and Engineering

First Page

2417

Last Page

2454

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