Single-Cell Analysis Using Hyperspectral Imaging Modalities

Authors

Nishir Mehta, Department of Mechanical Engineering, Louisiana State University, Baton Rouge, LA 70803.
Shahensha Shaik, Department of Mechanical Engineering, Louisiana State University, Baton Rouge, LA 70803.
Ram Devireddy, Department of Mechanical Engineering, Louisiana State University, Baton Rouge, LA 70803 e-mail: .
Manas Ranjan Gartia, Department of Mechanical Engineering, Louisiana State University, Baton Rouge, LA 70803.

Document Type

Article

Publication Date

2-1-2018

Abstract

Almost a decade ago, hyperspectral imaging (HSI) was employed by the NASA in satellite imaging applications such as remote sensing technology. This technology has since been extensively used in the exploration of minerals, agricultural purposes, water resources, and urban development needs. Due to recent advancements in optical re-construction and imaging, HSI can now be applied down to micro- and nanometer scales possibly allowing for exquisite control and analysis of single cell to complex biological systems. This short review provides a description of the working principle of the HSI technology and how HSI can be used to assist, substitute, and validate traditional imaging technologies. This is followed by a description of the use of HSI for biological analysis and medical diagnostics with emphasis on single-cell analysis using HSI.

Publication Source (Journal or Book title)

Journal of biomechanical engineering

First Page

0208021

Last Page

02080216

Recommended Citation

Mehta, N., Shaik, S., Devireddy, R., & Gartia, M. R. (2018). Single-Cell Analysis Using Hyperspectral Imaging Modalities. Journal of biomechanical engineering, 140 (2), 0208021-02080216. https://doi.org/10.1115/1.4038638