The stereoselective synthesis of the butyrolactone-bridged [8-5-5] tricyclic ring systems of (+/-)-asteriscanolide via the titanium-mediated Hetero-Pauson-Khand reaction

Identifier

etd-03112005-165301

Author

Mohamed G. Sherriff, Louisiana State University and Agricultural and Mechanical CollegeFollow

Degree

Doctor of Philosophy (PhD)

Department

Chemistry

Document Type

Dissertation

Abstract

The stereoselective construction of the tricyclic ring system of asteriscanolide from cyclooctadiene has been achieved. The synthesis involves two main steps; the synthesis of the aldehyde precursor(5)and the titanium-mediated cabocyclization of 5 to make the three rings of 43 stereoselectively.

Date

2005

Document Availability at the Time of Submission

Release the entire work immediately for access worldwide.

Recommended Citation

Sherriff, Mohamed G., "The stereoselective synthesis of the butyrolactone-bridged [8-5-5] tricyclic ring systems of (+/-)-asteriscanolide via the titanium-mediated Hetero-Pauson-Khand reaction" (2005). LSU Doctoral Dissertations. 2454.
https://repository.lsu.edu/gradschool_dissertations/2454

Committee Chair

Graca Vicente

DOI

10.31390/gradschool_dissertations.2454