Title
Concise enantioselective total synthesis of neopeltolide macrolactone highlighted by ether transfer
Document Type
Article
Publication Date
12-1-2008
Abstract
(Chemical Equation Presented) A concise total synthesis of neopeltolide macrolactone has been accomplished in 14 steps in the longest linear sequence, 15 steps overall from commercially available materials. The present synthesis was highlighted by successful exploitation of ether transfer methodology and a radical cyclization reaction to directly establish the requisite stereochemistry of the tetrahydropyran core. © 2008 American Chemical Society.
Publication Source (Journal or Book title)
Organic Letters
First Page
5047
Last Page
5050
Recommended Citation
Kartika, R., Gruffi, T., & Taylor, R. (2008). Concise enantioselective total synthesis of neopeltolide macrolactone highlighted by ether transfer. Organic Letters, 10 (21), 5047-5050. https://doi.org/10.1021/ol802254z