Title
Functionalization of Silyldienol Ethers at the γ-Position via 2-Silyloxypentadienyl Cations
Document Type
Article
Publication Date
3-4-2016
Abstract
© 2016 American Chemical Society. This report describes Brønsted acid catalyzed de novo synthesis of silyldienol ethers bearing tetrasubstituted double bonds via an intermediacy of 2-silyloxypentadienyl cations. The reactivity of these novel cationic intermediates could be modulated and harnessed toward direct nucleophilic additions regioselectively at the γ-position to produce highly functionalized silyldienol ethers with tunable control of the resulting double bond geometry.
Publication Source (Journal or Book title)
Organic Letters
First Page
1084
Last Page
1087
Recommended Citation
Ayala, C., Dange, N., Stepherson, J., Henry, J., Fronczek, F., & Kartika, R. (2016). Functionalization of Silyldienol Ethers at the γ-Position via 2-Silyloxypentadienyl Cations. Organic Letters, 18 (5), 1084-1087. https://doi.org/10.1021/acs.orglett.6b00196