Title
tert-Butyl (2S)-2-{3-[(R)-bis-(tert-but-oxy-carbon-yl)amino]-2-oxopiperidin-1-yl}-3-methyl-butano-ate
Document Type
Article
Publication Date
11-1-2011
Abstract
The title compound, C(24)H(42)N(2)O(7), is a chiral lactam-constrained amino acid with a six-membered ring backbone and isopropyl and tert-butyl ester side chains. The conformation of the six-membered ring can be described as a half chair, with two CH(2) C atoms lying 0.443 (1) and -0.310 (1) Å out of the best plane of the other four atoms (mean deviation = 0.042 Å). Both N atoms are sp(2) hybridized, lying 0.0413 (9) and 0.067 (1) Å out of the planes defined by the three C atoms bonded to them. The absolute configuration was determined, based on resonant scattering of light atoms in Cu Kα radiation.
Publication Source (Journal or Book title)
Acta crystallographica. Section E, Structure reports online
First Page
o3057
Recommended Citation
Kangas, M. J., Fronczek, F. R., & Watkins, S. F. (2011). tert-Butyl (2S)-2-{3-[(R)-bis-(tert-but-oxy-carbon-yl)amino]-2-oxopiperidin-1-yl}-3-methyl-butano-ate. Acta crystallographica. Section E, Structure reports online, 67 (Pt 11), o3057. https://doi.org/10.1107/S1600536811043212