"New Phytotoxic Cassane-like Diterpenoids from Eragrostis plana" by Adriana Favaretto, Charles L. Cantrell et al.

Faculty Publications

Title

New Phytotoxic Cassane-like Diterpenoids from Eragrostis plana

Authors

Adriana Favaretto, Agronomy Graduate Program , University of Passo Fundo , Passo Fundo , Rio Grande do Sul 99052-900 , Brazil.
Charles L. Cantrell, Natural Products Utilization Research Unit , United States Department of Agriculture, USDA-ARS , University , Mississippi 38677 , United States.
Frank R. Fronczek, Department of Chemistry , Louisiana State University , Baton Rouge , Louisiana 70803 , United States.
Stephen O. Duke, Natural Products Utilization Research Unit , United States Department of Agriculture, USDA-ARS , University , Mississippi 38677 , United States.
David E. Wedge, Natural Products Utilization Research Unit , United States Department of Agriculture, USDA-ARS , University , Mississippi 38677 , United States.
Abbas Ali, National Center for Natural Products Research , The University of Mississippi , University , Mississippi 38677 , United States.
Simone M. Scheffer-Basso, Agronomy Graduate Program , University of Passo Fundo , Passo Fundo , Rio Grande do Sul 99052-900 , Brazil.

Document Type

Article

Publication Date

2-20-2019

Abstract

Eragrostis plana (Nees) is an allelopathic plant with invasive potential in South American pastures. To isolate and identify phytotoxic compounds from leaves and roots of E. plana, a bioassay-directed isolation of the bioactive constituents was performed. This is the first report on a new diterpene carbon skeleton, neocassane, and of three new neocassane diterpenes, neocassa-1,12(13),15-triene-3,14-dione, 1; 19-norneocassa-1,12(13),15-triene-3,14-dione, 2; and 14-hydroxyneocassa-1,12(17),15-triene-3-one, 3, identified from the roots. Compounds 1, 2, and 3 inhibited the growth of duckweed by 50% at concentrations of 109 ± 28, 200 ± 37, and 59 ± 15 μM, respectively. Compound 2 was fungicidal to Colletotrichum fragariae, Colletotrichum acutatum, and Colletotrichum gloeosporioides. The compounds identified here could explain the allelopathy of E. plana. The description of the newly discovered compounds, besides contributing to the chemical characterization of the species, may be the first step in the study of the potential of these compounds as bioherbicides.

Publication Source (Journal or Book title)

Journal of agricultural and food chemistry

First Page

1973

Last Page

1981

Recommended Citation

Favaretto, A., Cantrell, C. L., Fronczek, F. R., Duke, S. O., Wedge, D. E., Ali, A., & Scheffer-Basso, S. M. (2019). New Phytotoxic Cassane-like Diterpenoids from Eragrostis plana. Journal of agricultural and food chemistry, 67 (7), 1973-1981. https://doi.org/10.1021/acs.jafc.8b06832

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