Title
A convenient preparation of xanthene dyes
Document Type
Article
Publication Date
8-19-2005
Abstract
A facile synthetic route utilizing readily available reagents affords a series of regioisomerically pure xanthene dye derivatives. Advantages include relatively mild conditions and good to excellent yields. Nonpolar, highly crystalline intermediates are isolable by standard chromatographic techniques. The intermediates are in the requisite xanthene oxidation state, thus avoiding the need for relatively inefficient oxidation chemistry and/or harsh conditions. During the course of this work, a new boron-mediated 1,2-aryl migration reaction was discovered.
Publication Source (Journal or Book title)
The Journal of organic chemistry
First Page
6907
Last Page
12
Recommended Citation
Yang, Y., Escobedo, J. O., Wong, A., Schowalter, C. M., Touchy, M. C., Jiao, L., Crowe, W. E., Fronczek, F. R., & Strongin, R. M. (2005). A convenient preparation of xanthene dyes. The Journal of organic chemistry, 70 (17), 6907-12. https://doi.org/10.1021/jo051002a