Title
Fluorescence-detected circular dichroism studies of serum albumins
Document Type
Article
Publication Date
8-1-1987
Abstract
Multidimensional fluorescence-detected circular dichroism (FDCD) is used to investigate the binding of bilirubin to four mammalian serum albumins. It is shown that the complexes formed with the albumins have distinctly different FDCD spectra. The effect of the pH-dependent transition from basic to acidic conditions on the complexes is examined. The binding of warfarin to albumin is also presented to demonstrate the general analytical utility of the multidimensional FDCD measurement for biochemical analysis. © 1987.
Publication Source (Journal or Book title)
Analytical Biochemistry
First Page
466
Last Page
473
Recommended Citation
Thomas, M., Patonay, G., & Warner, I. (1987). Fluorescence-detected circular dichroism studies of serum albumins. Analytical Biochemistry, 164 (2), 466-473. https://doi.org/10.1016/0003-2697(87)90520-3