Title
Influence of Alcohols on the β-Cyclodextrin/Acridine Complex
Document Type
Article
Publication Date
1-1-1993
Abstract
The apparent formation constant calculated for the β-cyclodextrin/acridine (β-CD/ACR) complex (287 M−1) reveals a weak association in aqueous solution. An additional weakening of the binding strength between β-CD and ACR, and subsequent reduction in the previously reported quenching of ACR caused by β-CD, is observed upon interaction of the complex with selected straight-chain and branched alcohols. Nuclear magnetic resonance data suggest that the equilibrium involves the formation of ternary complexes. This equilibrium apparently leaves a greater number of ACR species accessible to the bulk aqueous environment, resulting in a consequent decrease in the total amount of ACR quenched. Specific mechanisms of interaction are further examined through information provided by steady-state fluorescence and fluorescence lifetime analysis. © 1993, American Chemical Society. All rights reserved.
Publication Source (Journal or Book title)
Journal of the American Chemical Society
First Page
292
Last Page
298
Recommended Citation
Schuette, J., Ndou, T., de la Peña, A., Mukundan, S., & Warner, I. (1993). Influence of Alcohols on the β-Cyclodextrin/Acridine Complex. Journal of the American Chemical Society, 115 (1), 292-298. https://doi.org/10.1021/ja00054a042