Title

Chiral Separations Using Micellar Electrokinetic Capillary Chromatography and a Polymerized Chiral Micelle

Document Type

Article

Publication Date

11-1-1994

Abstract

A chiral micelle polymer, poly(sodium N-undecylenyl-1-valinate), has been synthesized and used for chiral separation in micellar electrokinetic capillary chromatography. The chiral separations of (±)-1,1′-bi-2-naphthol and d,l-laudanosine were achieved through the addition of this chiral micelle polymer to buffer solutions. A comparison study of separations was conducted on the micelle polymer and the corresponding nonpolymerized surfactant under the same separation conditions. Several advantages of using the micelle polymer are noted. In addition, a model of micelle-solute interaction is proposed to rationalize the improved chiral separation ability of micelle polymers. © 1994, American Chemical Society. All rights reserved.

Publication Source (Journal or Book title)

Analytical Chemistry

First Page

3773

Last Page

3776

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