Document Type

Article

Publication Date

7-20-2006

Abstract

The synthesis and biological evaluation of a series of analogues of manzamine A, representing partial structures of the pentacyclic ABCDE diamine core, is described. All new compounds were screened against Plasmodium falciparum and demonstrated attenuated antimalarial activity relative to that of manzamine A. © 2006 American Chemical Society.

Publication Source (Journal or Book title)

Organic Letters

First Page

3407

Last Page

3409

COinS