Document Type
Article
Publication Date
10-1-2004
Abstract
A single droplet generator was coupled with a rotating ball inlet matrix-assisted laser desorption/ionization (MALDI) time of flight (TOF) mass spectrometer. Single droplets with 100 picoliter volume were ejected by a piezoelectric-actuated droplet generator and deposited onto a matrix-coated rotating stainless steel ball at atmospheric pressure. The single droplet deposit was transported to the vacuum side of the instrument where ionization was accomplished using a UV pulsed laser. Using this on-line interface, it was possible to obtain protonated molecule signal from as little as 10 fmol analyte. © 2004 American Society for Mass Spectrometry.
Publication Source (Journal or Book title)
Journal of the American Society for Mass Spectrometry
First Page
1471
Last Page
1477
Recommended Citation
Zhang, X., Narcisse, D., & Murray, K. (2004). On-line single droplet deposition for MALDI mass spectrometry. Journal of the American Society for Mass Spectrometry, 15 (10), 1471-1477. https://doi.org/10.1016/j.jasms.2004.06.016