Title
Integrated microfluidic system for proteomics using mixed-scale structures and MALDI-TOF-MS
Document Type
Conference Proceeding
Publication Date
1-1-2006
Abstract
A typical sample processing pipeline for proteomics entails a series of laborious and low throughput steps that often results in long analysis times and sample loss, thereby affecting the overall efficiency and outcome of the measurement. We have assembled a polymerbased microfluidic system that includes most of the protein processing steps into a single wafer and can be interfaced to several different mass spectrometer platforms for protein identification. The system was fabricated via micro-replication technologies from polymers and possessed the ability to analyze ∼900 proteins in a single sample in an automated fashion with a total processing time <1 h. © 2006 Society for Chemistry and Micro-Nano Systems.
Publication Source (Journal or Book title)
Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences
First Page
1570
Last Page
1572
Recommended Citation
Musyimi, H., Shadpour, H., Chen, G., McCarley, R., Murray, K., & Soper, S. (2006). Integrated microfluidic system for proteomics using mixed-scale structures and MALDI-TOF-MS. Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 1570-1572. Retrieved from https://repository.lsu.edu/chemistry_pubs/1023