"Crawling with virus: Translational insights from a neonatal mouse mode" by Dahui You, Jordy Saravia et al.

Faculty Publications

Title

Crawling with virus: Translational insights from a neonatal mouse model on the pathogenesis of respiratory syncytial virus in infants

Authors

Dahui You, University of Tennessee Health Science Center
Jordy Saravia, University of Tennessee Health Science Center
David Siefker, University of Tennessee Health Science Center
Bishwas Shrestha, University of Tennessee Health Science Center
Stephania A. Cormier, University of Tennessee Health Science Center

Document Type

Article

Publication Date

1-1-2016

Abstract

© 2015, American Society for Microbiology. The infant immune response to respiratory syncytial virus (RSV) remains incompletely understood. Here we review the use of a neonatal mouse model of RSV infection to mimic severe infection in human infants. We describe numerous age-specific responses, organized by cell type, observed in RSV-infected neonatal mice and draw comparisons (when possible) to human infants.

Publication Source (Journal or Book title)

Journal of Virology

First Page

Last Page

Recommended Citation

You, D., Saravia, J., Siefker, D., Shrestha, B., & Cormier, S. (2016). Crawling with virus: Translational insights from a neonatal mouse model on the pathogenesis of respiratory syncytial virus in infants. Journal of Virology, 90 (1), 2-4. https://doi.org/10.1128/JVI.01026-15

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