Title
Smaller is better for antibiotic discovery
Document Type
Article
Publication Date
6-19-2009
Abstract
A recent study demonstrates the use of fragment-based drug discovery and virtual screening to develop inhibitors of biotin carboxylase that exhibit antibacterial activity. The work not only further validates biotin carboxylase as a target for antibiotic research but also provides a framework for using fragment-based drug discovery in antibiotic development.
Publication Source (Journal or Book title)
ACS chemical biology
First Page
397
Last Page
9
Recommended Citation
Waldrop, G. L. (2009). Smaller is better for antibiotic discovery. ACS chemical biology, 4 (6), 397-9. https://doi.org/10.1021/cb900122j
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