Ergoladinine, an ergot alkaloid

Ladislav Cvak, Teva Pharmaceutical Industries Ltd.
Josef Minář, Teva Pharmaceutical Industries Ltd.
Svetlana Pakhomova, University of Chemistry and Technology, Prague
Jan Ondráček, University of Chemistry and Technology, Prague
Bohumil Kratochvíl, University of Chemistry and Technology, Prague
Petr Sedmera, Institute of Microbiology of the Academy of Sciences of the Czech Republic
Vladimír Havlíček, Institute of Microbiology of the Academy of Sciences of the Czech Republic
Alexandr Jegorov, Teva Pharmaceutical Industries Ltd.

Abstract

A new natural peptide ergot alkaloid, ergoladinine, containing methionine, has been isolated from sclerotia of the field-growing parasitic fungus, Claviceps purpurea. Its structure was deduced from the X-ray analysis, NMR and mass spectral data. Copyright © 1996 Elsevier Science Ltd. All rights reserved.