Production of transgenic and knockout pigs by somatic cell nuclear transfer

Document Type

Article

Publication Date

7-27-2012

Abstract

Xenotransplantation is one alternative to transplantation of human organs which has been investigated. It is generally accepted that the pig represents the most logical choice of animals to serve as organ donors for xenotransplantation. Moreover, the implementation of cloning by somatic cell nuclear transfer (SCNT) and transgenic techniques have resulted in the production of numerous transgenic pigs than can be used for xenotransplantation purposes as well as models for human diseases. © 2012 Springer Science+Business Media, LLC.

Publication Source (Journal or Book title)

Methods in Molecular Biology

First Page

105

Last Page

123

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