Graft reactions after keratoplasty for keratoconus

Document Type

Article

Publication Date

1-1-1974

Abstract

Graft reactions occur in approximately 35% of grafts after keratoplasty for keratoconus. If not promptly recognized and treated, graft reactions destroy previously successful grafts. Symptoms of a red eye, decreased vision, or vague ocular discomfort frequently herald graft reactions. These reactions can be recognized by the following triad: local bulbar conjunctival hyperemia, keratic precipitates on the corneal endothelium, and localized graft edema. Prompt initiation of intensive corticosteroid therapy leads to complete recovery in early cases. Ten percent of otherwise successful grafts for keratoconus are lost most probably because of the lack of prompt recognition and for inadequate therapy of graft reactions. The recipients of living cryopreserved corneal tissue had the same graft reaction rate, proportion of grafts remaining clear, and final clear grafts over the three-year follow-up as those with fresh refrigerated tissue. © 1974.

Publication Source (Journal or Book title)

American Journal of Ophthalmology

First Page

543

Last Page

547

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