Document Type
Article
Publication Date
1-1-2018
Abstract
The oviduct is a tubular organ comprising three distinct anatomical regions (the infundibulum, the ampulla and the isthmus) connecting the ovary and the uterus. Oviductal function is regulated by ovarian hormones, gametes, and embryo-derived factors, for optimally facilitating key reproductive events. A cross-talk is established between the oviduct and the gametes and embryo and this dialogue shapes the microenvironment in which gamete transport, fertilization, and early embryonic development occur. This review aims to address each participant in this conversation in a holistic manner by delineating several advances in the field within the greater context of understanding how oviduct-gamete and oviduct-embryo dialogue shape reproductive success and furthermore how this knowledge can be applied in vitro.
Publication Source (Journal or Book title)
Animal Reproduction
First Page
751
Last Page
764
Recommended Citation
Fernandez-Fuertes, B., Rodríguez-Alonso, B., Sánchez, J., Simintiras, C., Lonergan, P., & Rizos, D. (2018). Looking at the big picture: Understanding how the oviduct's dialogue with gametes and the embryo shapes reproductive success. Animal Reproduction, 15, 751-764. https://doi.org/10.21451/1984-3143-AR2018-0036