Abnormal red blood cell ion transport and hypertension: The people’s gas company study

Document Type

Article

Publication Date

1-1-1982

Abstract

A population-based survey of 134 white men, recruited from the Chicago People’s Gas Company labor force, was carried out to examine the association between sodium-lithium (Na-Li) countertransport and hypertension. Of the 134 participants in this industry-sponsored periodic health examination, 64 were normotensive and 70 were either taking antihypertensive medications or had a systolic pressure ≥ 140 or a diastolic pressure ≥ 90 mm Hg. The hypertensives were older and more overweight. Countertransport was significantly higher in hypertensives than in normotensives. Among the three subgroups of hypertensives - untreated borderline (140/90 to 160/95 mm Hg), untreated definite (over 160/95 mm Hg), and treated - an increase in countertransport was consistently observed, significant for the latter two groups. The relationship between countertransport and hypertension was independent of overweight, with countertransport being significantly related to both blood pressure and overweight. Altered ion transport may play an important role in the etiology and/or pathophysiology of hypertension. © 1983 American Heart Association, Inc.

Publication Source (Journal or Book title)

International Journal of Rehabilitation Research

First Page

363

Last Page

367

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