The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis

Authors

W. K. Chung, Vagelos College of Physicians and Surgeons
A. Luke, Loyola University Medical Center
R. S. Cooper, Loyola University Medical Center
C. Rotini, Loyola University Medical Center
A. Vidal-Puig, Beth Israel Deaconess Medical Center
M. Rosenbaum, Vagelos College of Physicians and Surgeons
D. Gordon, Rockefeller University
S. M. Leal, Rockefeller University
S. Caprio, Yale School of Medicine
R. Goldsmith, Vagelos College of Physicians and Surgeons
A. L. Andreu, Vagelos College of Physicians and Surgeons
C. Bruno, Vagelos College of Physicians and Surgeons
S. DiMauro, Vagelos College of Physicians and Surgeons
M. Heo, Vagelos College of Physicians and Surgeons
W. L. Lowe, Vagelos College of Physicians and Surgeons
B. B. Lowell, Beth Israel Deaconess Medical Center
D. B. Allison, Vagelos College of Physicians and Surgeons
R. L. Leibel, Vagelos College of Physicians and Surgeons

Document Type

Article

Publication Date

6-1-1999

Abstract

The biological role(s) proposed for UCP3 in energy homeostasis have been based primarily upon amino acid sequence homology to UCP1. Spontaneous mutations of UCP3 have been described in humans, but not in rodents. The functional consequences—or lack thereof—of these mutations in humans will be of great importance in elucidating the biology of this protein. The results of two such studies are summarized here. © 1999 Stockton Press. All rights reserved.

Publication Source (Journal or Book title)

International Journal of Obesity

First Page

S49

Last Page

S50

Recommended Citation

Chung, W., Luke, A., Cooper, R., Rotini, C., Vidal-Puig, A., Rosenbaum, M., Gordon, D., Leal, S., Caprio, S., Goldsmith, R., Andreu, A., Bruno, C., DiMauro, S., Heo, M., Lowe, W., Lowell, B., Allison, D., & Leibel, R. (1999). The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis. International Journal of Obesity, 23, S49-S50. https://doi.org/10.1038/sj.ijo.0800945