Preparation, characterization and in vitro antitumoral activity of a nanosize liposome complex encapsulated polyoxotungstate K6H 2[CoW11TiO40]

Authors

Yong Yang, Northeast Normal University
Jianghua He, Northeast Normal University
Xiaohong Wang, Northeast Normal University
Bin Li, Northeast Normal University
Jingfu Liu, Northeast Normal University

Document Type

Article

Publication Date

2-1-2004

Abstract

The nanosize liposome complex-encapsulated polyoxotungstate K 6H2[CoW11TiO40] has been prepared and structurally characterized by i.r., u.v.-vis and e.s.r. spectra. The particle size of the liposome complex-encapsulated K6H 2[CoW11TiO40], is distributed in two uncontinuous limits in which 98.9% of particles distributed in the limit of 62.8-76.7 nm, average diameter, is 69.4 nm. The result shows that the polyoxotungstate retains the parent structure after being encapsulated by liposome, and that liposomal encapsulation increase the antitumoral activity of the polyoxometalate.

Publication Source (Journal or Book title)

Transition Metal Chemistry

First Page

96

Last Page

99

Recommended Citation

Yang, Y., He, J., Wang, X., Li, B., & Liu, J. (2004). Preparation, characterization and in vitro antitumoral activity of a nanosize liposome complex encapsulated polyoxotungstate K6H 2[CoW11TiO40]. Transition Metal Chemistry, 29 (1), 96-99. https://doi.org/10.1023/B:TMCH.0000014494.72867.c5