Synthesis, characterization and the biological activity of a polyoxometalate-loaded nanosize-liposome complex

Document Type

Article

Publication Date

10-1-2005

Abstract

The polyoxometalate K6H[CoW11O39(CpTi)] (abbreviated as CoW11CpTi, Cp=η5-C5H 5) loaded nanosize-liposome complex has been prepared and structurally characterized by elemental analysis, IR and UV spectra. The particle size of the complex was distributed in the range of 100-250 nm with the average diameter of 132.6 nm. The result showed that the polyoxometalate retained the parent structure after being encapsulated by liposome and liposomal encapsulation increased the antitumoral activity of the polyoxometalate. © 2005 SIOC, CAS, & Wiley-VCH Verlag GmbH & Co. KGaA.

Publication Source (Journal or Book title)

Chinese Journal of Chemistry

First Page

1397

Last Page

1399

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