Dynamic kinetic resolution of 2-oxo-3-aryl-succinates by organocatalyzed aldolization

Document Type

Article

Publication Date

1-1-2007

Abstract

The dynamic kinetic resolution of 2-oxo-3-arylsuccinates was achieved via l-proline-catalyzed addition of acetone in acetonitrile at room temperature, providing the desired adduct in good yield with up to 87: 13 dr and high ee up to 99%. © The Royal Society of Chemistry.

Publication Source (Journal or Book title)

Chemical Communications

First Page

1284

Last Page

1286

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