Effects of (-)-epigallocatechin-3-gallate on interleukin-1beta expression in mouse wound healing
Document Type
Article
Publication Date
1-1-2009
Abstract
(-)-Epigallocatechin-3-gallate (EGCG), a main constituent of green tea polyphenols, plays important roles in antioxidative, anti-senescence, anti-tumor, anti-inflammation and bacterail action. In this study, effects of EGCG on the expression of IL-1beta gene and the IL-1beta level at wound sites during cutaneous wound healing were investigated with histological stain, ELISA and RT-PCR technique. The results show that EGCG (50 mg/L) inhibited the expression of IL-1beta gene and reduced the IL-beta level at wound sites at 72 h after cutaneous wound, but not change the expression of IL-1beta gene and the IL-1beta level at early stage (< or =24 h).
Publication Source (Journal or Book title)
Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology / Zhongguo xi bao sheng wu xue xue hui zhu ban
First Page
179
Last Page
185
Recommended Citation
Shen, Y., Li, W., Zhang, H., Li, B., Yuan, H., & Zhang, J. (2009). Effects of (-)-epigallocatechin-3-gallate on interleukin-1beta expression in mouse wound healing. Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology / Zhongguo xi bao sheng wu xue xue hui zhu ban, 42 (3-4), 179-185. Retrieved from https://repository.lsu.edu/ag_exst_pubs/672