New anti-HBV caryophyllane-type sesquiterpenoids from Euphorbia

Authors

Ying Tian, Beijing Institute of Radiation Medicine
Li Min Sun, Beijing Institute of Radiation Medicine
Bin Li, Beijing Institute of Radiation Medicine
Xi Qiao Liu, Beijing Institute of Radiation Medicine
Jun Xing Dong, Beijing Institute of Radiation Medicine

Document Type

Article

Publication Date

1-1-2011

Abstract

Activity-guided fractionation of Euphorbia humifusa for anti-HBV activity led to the isolation of two novel sesquiterpenoids, named humifusane A (1) and humifusane B (2). Their structures were elucidated by spectral data to show that they have a caryophyllane-type precursor structure. The two new sesquiterpenoids showed anti-HBV activities through specifically inhibiting the secretion of HBsAg in HepG2.2.15. © 2010 Elsevier B.V. All rights reserved.

Publication Source (Journal or Book title)

Fitoterapia

First Page

251

Last Page

254

Recommended Citation

Tian, Y., Sun, L., Li, B., Liu, X., & Dong, J. (2011). New anti-HBV caryophyllane-type sesquiterpenoids from Euphorbia. Fitoterapia, 82 (2), 251-254. https://doi.org/10.1016/j.fitote.2010.10.005