Nucleophilic addition of benzimidazoles to alkynyl bromides/palladium- catalyzed intramolecular C-H vinylation: Synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines
Document Type
Article
Publication Date
2-1-2013
Abstract
An efficient "one-pot" route for the synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines has been developed via nucleophilic addition of 2-aryl benzimidazoles to alkynyl bromides and subsequent palladium-catalyzed intramolecular C-H vinylation. © 2012 American Chemical Society.
Publication Source (Journal or Book title)
Journal of Organic Chemistry
First Page
1242
Last Page
1248
Recommended Citation
Peng, J., Shang, G., Chen, C., Miao, Z., & Li, B. (2013). Nucleophilic addition of benzimidazoles to alkynyl bromides/palladium- catalyzed intramolecular C-H vinylation: Synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines. Journal of Organic Chemistry, 78 (3), 1242-1248. https://doi.org/10.1021/jo302471z
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