Nucleophilic addition of benzimidazoles to alkynyl bromides/palladium- catalyzed intramolecular C-H vinylation: Synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines

Document Type

Article

Publication Date

2-1-2013

Abstract

An efficient "one-pot" route for the synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines has been developed via nucleophilic addition of 2-aryl benzimidazoles to alkynyl bromides and subsequent palladium-catalyzed intramolecular C-H vinylation. © 2012 American Chemical Society.

Publication Source (Journal or Book title)

Journal of Organic Chemistry

First Page

1242

Last Page

1248

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