Modified "DMC" technique for stretching DNA molecules

Document Type

Article

Publication Date

12-1-1999

Abstract

A modified "dynamic molecular combing"(DMC) technique used for stretching double-stranded DNA is reported. DNA molecules were stretched on the silanized mica surface by this technique, its speed being precisely controlled with a computer. This approach combined the precise DNA stretching method with high resolution AFM imaging at nanometer scale, thus making it useful for DNA alignment manipulation and subsequent gene research.

Publication Source (Journal or Book title)

Nuclear Science and Techniques/Hewuli

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