Synthesis and antitumor activity of cyclopentadienyltitanium substituted polyoxotungstate [CoW11O39(CpTi)]^7- (Cp=η⁵-C5H5)

Authors

Xiaohong Wang, Northeast Normal University
Jingfu Liu, Northeast Normal University
Jianxin Li, Northeast Normal University
Yong Yang, Northeast Normal University
Jutao Liu, Northeast Normal University
Bin Li, Northeast Normal University
Michael T. Pope, Georgetown University

Document Type

Article

Publication Date

3-1-2003

Abstract

A novel polyoxotungstate [CoW11O39(CpTi)]7- (Cp=η5-C5H5) has been prepared. This complex exhibits the highest antitumor activity in vitro among the cyclopentadienyltitanium substituted polyoxometalates investigated and has a remarkable inhibitory action on three types of human cancer cells, SSMC-7721, HL-60 and HLC, in vivo. © 2002 Published by Elsevier Science Inc.

Publication Source (Journal or Book title)

Journal of Inorganic Biochemistry

First Page

279

Last Page

284

Recommended Citation

Wang, X., Liu, J., Li, J., Yang, Y., Liu, J., Li, B., & Pope, M. (2003). Synthesis and antitumor activity of cyclopentadienyltitanium substituted polyoxotungstate [CoW11O39(CpTi)]^7- (Cp=η⁵-C5H5). Journal of Inorganic Biochemistry, 94 (3), 279-284. https://doi.org/10.1016/S0162-0134(02)00631-1