Purpose: To develop a simple model of therapeutic and stray absorbed dose for a variety of treatment machines and techniques without relying on proprietary machine-specific parameters. Methods: Dosimetry measurements conducted in this study and from the literature were used to develop an analytical model of absorbed dose from a variety of treatment machines and techniques in the 6 to 25 MV interval. A modified one-dimensional gamma-index analysis was performed to evaluate dosimetric accuracy of the model on an independent dataset consisting of measured dose profiles from seven treatment units spanning four manufacturers. Results: The average difference between the calculated and measured absorbed dose values was 9.9% for those datasets on which the model was trained. Additionally, these results indicate that the model can provide accurate calculations of both therapeutic and stray radiation dose from a wide variety of radiotherapy units and techniques. Conclusions: We have developed a simple analytical model of absorbed dose from external beam radiotherapy treatments in the 6 to 25 MV beam energy range. The model has been tested on measured data from multiple treatment machines and techniques, and is broadly applicable to contemporary external beam radiation therapy.
Publication Source (Journal or Book title)
Schneider, C., Newhauser, W., Wilson, L., Schneider, U., Kaderka, R., Miljanic, S., Kneževic, Ž., Stolarcyzk, L., Durante, M., & Harrison, R. (2017). A descriptive and broadly applicable model of therapeutic and stray absorbed dose from 6 to 25 MV photon beams:. Medical Physics, 44 (7), 3805-3814. https://doi.org/10.1002/mp.12286