A molecular dynamics simulation study on the effect of methanol on the structural characteristics of lipid bilayerS

Document Type

Conference Proceeding

Publication Date

12-1-2005

Abstract

To further our understanding on the water permeation process through a lipid bilayer membrane in the presence of a commonly used cryoprotective agent (methanol), we performed detailed molecular dynamics simulation (MD) studies. The MD simulations analyzed the influence of methanol (12 mol %) on the structure of a fully hydrated dipalmitoylphosphatidylcholine (DPPC) in the fluid phase and under equilibrium conditions at 323K. Copyright © 2005 by ASME.

Publication Source (Journal or Book title)

Proceedings of the ASME Summer Heat Transfer Conference

First Page

811

Last Page

815

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