A practical synthesis of (11-mercaptoundecyloxy)-triethylene glycol: A valuable precursor for multicomponent self-assembled monolayers
HSC11EG3OH (1) is an important component for formation of protein-resistant self-assembled monolayers on gold. Chromatography of small molecules containing oligoethylene units, such as 1 and its synthetic intermediates, are typically complicated by smearing on TLC, making separation tedious. We have developed a convenient modification for synthesis of 1 by using a UV-visible intermediate facilitating column chromatography of the desired compound.
Publication Source (Journal or Book title)
Journal of Sulfur Chemistry
Reed, N., & Spivak, D. (2009). A practical synthesis of (11-mercaptoundecyloxy)-triethylene glycol: A valuable precursor for multicomponent self-assembled monolayers. Journal of Sulfur Chemistry, 30 (5), 477-480. https://doi.org/10.1080/17415990902913362