Molecular recognition study on supramolecular system(XII) - Molecular recognition of 4-substituted phenols by cyclodextrins and binuclear Cu( II) complexes with cyclodextrins

Document Type

Article

Publication Date

12-1-1997

Abstract

The spectrophotometric titrations have been performed in aqueous solutions with different pH values at 25.0°C to give the stability constants (lgK s) for inclusion complexation of various 4-substituted phenols with α-, β- and γ- cyclodextrins and binuclear copper ( II )-α, β-cyclodextrins complexes. The stoichiometry of the supramolecular complexes formed is 1:1 for all the host cyclodextrins and binuclear copper( II )-cyclodextrins complexes inclusion complexation with various guest 4-substituted phenols. The molecular recognition mechanism for 4-substituted phenols of the cyclodextrins and binuclear Cu( II ) complexes with cyclodextrins is discussed from the viewpoint of the size/shape-fit, multiple recognition, induced-fit relationship between the host cavity and the guest molecules. The results obtained indicate that the binuclear Cu( II ) complex with β-cyclodextrin possesses the special binding ability and molecular selectivity for 4-substituted phenols.

Publication Source (Journal or Book title)

Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao/ Chemical Journal of Chinese Universities

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