Neurotensin-induced polydipsia: a structure-activity study
Document Type
Article
Publication Date
5-15-1989
Abstract
Neurotensin (NT) and equimolar concentrations of NT fragments were microinjected into the lateral cerebral ventricle of water-deprived rats. NT (10μg) increased water intake 146% in the first 15 min following injection. While NT1-11 and NT10-13 had no effect on water intake, NT8-13 increased water intake 101%. The polydipsia produced by NT8-13 was statistically equivalent to that produced by NT. The results are discussed in relation to a proposed model of the NT receptor. © 1989.
Publication Source (Journal or Book title)
Brain Research
First Page
188
Last Page
191
Recommended Citation
Hawkins, M., Baker, J., & Baumeister, A. (1989). Neurotensin-induced polydipsia: a structure-activity study. Brain Research, 487 (1), 188-191. https://doi.org/10.1016/0006-8993(89)90957-8
COinS