Consuming a ketogenic diet leads to altered hypoglycemiccounter-regulation in mice

Authors

Christopher D. Morrison, Pennington Biomedical Research Center
Cristal M. Hill, Pennington Biomedical Research Center
Marina A. DuVall, Pennington Biomedical Research Center
Carolyn E. Coulter, Pennington Biomedical Research Center
Jasmin L. Gosey, Pennington Biomedical Research Center
Matthew J. Herrera, Pennington Biomedical Research Center
Lauren E. Maisano, Pennington Biomedical Research Center
Hunter X. Sikaffy, Pennington Biomedical Research Center
David H. McDougal, Pennington Biomedical Research Center

Document Type

Article

Publication Date

5-1-2020

Abstract

Ketogenic diets (KDs) are becoming increasingly popular for the treatment of diabetes, yet they are associated with increased frequency of hypoglycemia. Here we report that mice fed a KD display blunted glucagon release to hypoglycemia and neuroglucopenia, suggesting that consuming a KD may increase the risk for iatrogenic hypoglycemia.

Recommended Citation

Morrison, C., Hill, C., DuVall, M., Coulter, C., Gosey, J., Herrera, M., Maisano, L., Sikaffy, H., & McDougal, D. (2020). Consuming a ketogenic diet leads to altered hypoglycemiccounter-regulation in mice. Retrieved from https://repository.lsu.edu/pbrc_basic_science_pubs/257