On the possible application of a microscale thermocouple to measure intercellular ICE formation in cells embedded in an extracellular matrix

Document Type

Conference Proceeding

Publication Date

1-1-2004

Abstract

To optimize a freezing protocol for tissue systems, knowledge of intercellular ice formation and water transport is essential. Water transport during freezing can be measured using low temperature microscopy technique [1] and/or by differential scanning calorimetry method [2]. To study the formation of intracellular ice in cells embedded in an extra-cellular matrix we propose to design and develop an array of microscale thermocouples using microfabrication techniques [3]. The microfabricated thermocouples will be required to accurately measure the small temperature fluctuations in an embedded cell due to the formation of intracellular ice. Copyright © 2004 by ASME.

Publication Source (Journal or Book title)

American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD

First Page

705

Last Page

707

This document is currently not available here.

Share

COinS