On the possible application of a microscale thermocouple to measure intercellular ICE formation in cells embedded in an extracellular matrix
Document Type
Conference Proceeding
Publication Date
1-1-2004
Abstract
To optimize a freezing protocol for tissue systems, knowledge of intercellular ice formation and water transport is essential. Water transport during freezing can be measured using low temperature microscopy technique [1] and/or by differential scanning calorimetry method [2]. To study the formation of intracellular ice in cells embedded in an extra-cellular matrix we propose to design and develop an array of microscale thermocouples using microfabrication techniques [3]. The microfabricated thermocouples will be required to accurately measure the small temperature fluctuations in an embedded cell due to the formation of intracellular ice. Copyright © 2004 by ASME.
Publication Source (Journal or Book title)
American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD
First Page
705
Last Page
707
Recommended Citation
Kandra, D., & Devireddy, R. (2004). On the possible application of a microscale thermocouple to measure intercellular ICE formation in cells embedded in an extracellular matrix. American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD, 375 (1), 705-707. https://doi.org/10.1115/IMECE2004-60728