Mixed-scale fluidic system for point-of-care testing

Document Type

Conference Proceeding

Publication Date

1-1-2020

Abstract

We will report our recent efforts in developing reconfigurable modular fluidic systems consisting of task-specific modules integrated to a fluidic motherboard with the modules and motherboard made from thermoplastics via injection molding. Unique to our modular approach is that passive elements are used to simplify and make assembly repeatable, such as gasket-less interconnects and passive alignment structures. The modules can be used as standalone units as well. In the system we describe, both micro- and nanofluidic modules are used that can enrich nanoparticles (i.e., exosomes or viruses) from clinical samples and analyze their RNA cargo for disease diagnostics.

Publication Source (Journal or Book title)

MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

First Page

617

Last Page

618

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