Biosynthetic intermediates between coproporphyrinogen-III and protoporphyrin-IX
New syntheses of the isomeric tripropionic prophyrins (3a) and (3b) have been carried out, and the feeding of the porphyrinogens (5b) and (5c) (labelled with tritium) to an enzyme system from Euglena gracilis has confirmed the hypothesis that the 2-propionic acid side-chain is modified before the 4-substituent in the biosynthesis of protoporphyrinogen-IX (5d) from coproporphyrinogen-III (5a).
Publication Source (Journal or Book title)
Journal of the Chemical Society, Chemical Communications
Cavaleiro, J., Kenner, G., & Smith, K. (1973). Biosynthetic intermediates between coproporphyrinogen-III and protoporphyrin-IX. Journal of the Chemical Society, Chemical Communications (5), 183-184. https://doi.org/10.1039/C39730000183