A stochastic formulation for the description of the crystal size distribution in antisolvent crystallization processes

Document Type

Article

Publication Date

8-1-2010

Abstract

A stochastic approach to describe the crystal size distribution dynamics in antisolvent based crystal growth processes is here introduced. Fluctuations in the process dynamics are taken into account by embedding a deterministic model into a Fokker-Planck equation, which describes the evolution in time of the particle size distribution. The deterministic model used in this application is based on the logistic model, which shows to be adequate to suit the dynamics characteristic of the growth process. Validations against experimental data are presented for the NaCl-water-ethanol antisolvent crystallization system in a bench-scale fed-batch crystallization unit. © 2009 American Institute of Chemical Engineers.

Publication Source (Journal or Book title)

AIChE Journal

First Page

2077

Last Page

2087

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