A model-based approach for controlling particle size distribution in combined cooling-antisolvent crystallization processes
Document Type
Article
Publication Date
11-23-2018
Abstract
This article focuses on the design and implementation of model-based control strategies for real time control of crystal size distribution (CSD) in semi batch crystallization processes. The objective of the feedback controller is to reach a desired particle mean size while the standard deviation is controlled in a feedforward fashion. Alternative model-based control strategies are formulated and implemented for a target mean size. An image processing technique based on wavelet-fractal and energy signature analysis is employed to determine online CSD status for the controller's corrective actions. To validate the proposed model-based control strategies, unseeded crystallization of sodium chloride in water using ethanol as antisolvent is performed in an experimental bench-scale semi-batch crystallizer.
Publication Source (Journal or Book title)
Chemical Engineering Science
First Page
260
Last Page
272
Recommended Citation
Ghadipasha, N., Romagnoli, J., Tronci, S., & Baratti, R. (2018). A model-based approach for controlling particle size distribution in combined cooling-antisolvent crystallization processes. Chemical Engineering Science, 190, 260-272. https://doi.org/10.1016/j.ces.2018.06.032