Administration of copper oxide wire particles in a capsule or feed for gastrointestinal nematode control in goats

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Widespread anthelmintic resistance in small ruminants has necessitated alternative means of gastrointestinal nematode (GIN) control. The objective was to determine the effectiveness of copper oxide wire particles (COWP) administered as a gelatin capsule or in a feed supplement to control GIN in goats. In four separate experiments, peri-parturient does (n = 36), yearling does (n = 25), weaned kids (n = 72), and yearling bucks (n = 16) were randomly assigned to remain untreated or administered 2 g COWP in a capsule (in Experiments 1, 2, and 3) or feed supplement (all experiments). Feces and blood were collected every 7 days between Days 0 and 21 (older goats) or Day 42 (kids) for fecal egg counts (FEC) and blood packed cell volume (PCV) analyses. A peri-parturient rise in FEC was evident in the untreated does, but not the COWP-treated does (COWP × date, P < 0.02). In yearling does, FEC of the COWP-treated does tended to be lower than the untreated (COWP, P < 0.02). FEC of COWP-treated kids were reduced compared with untreated kids (COWP × date, P < 0.001). FEC of treated and untreated bucks were similar, but Haemonchus contortus was not the predominant nematode in these goats. However, total worms were reduced in COWP-fed bucks (P < 0.03). In summary, it appeared that COWP in the feed was as effective as COWP in a gelatin capsule to reduce FEC in goats. COWP administration may have a limited effect where H. contortus is not the predominant nematode.

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Veterinary Parasitology

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