Role of catalase in the virulence of Brucella melitensis in pregnant goats

Authors

Jason M. Gee, LSU Health Sciences Center - Shreveport
Michael E. Kovach, LSU Health Sciences Center - Shreveport
Vanessa K. Grippe, LSU Health Sciences Center - Shreveport
Sue Hagius, LSU Agricultural Center
Joel V. Walker, LSU Agricultural Center
Philip H. Elzer, LSU Agricultural Center
R. Martin Roop, The Brody School of Medicine

Document Type

Article

Publication Date

8-19-2004

Abstract

An isogenic katE mutant derived from virulent Brucella melitensis 16M displays hypersensitivity to hydrogen peroxide in disk sensitivity assays but retains the capacity to colonize pregnant goats and induce abortion. These experimental findings indicate that although the sole periplasmic catalase of Brucella melitensis functions as an antioxidant, this enzyme does not play a critical role in virulence in the natural host. © 2004 Elsevier B.V. All rights reserved.

Publication Source (Journal or Book title)

Veterinary Microbiology

First Page

111

Last Page

115

Recommended Citation

Gee, J., Kovach, M., Grippe, V., Hagius, S., Walker, J., Elzer, P., & Roop, R. (2004). Role of catalase in the virulence of Brucella melitensis in pregnant goats. Veterinary Microbiology, 102 (1-2), 111-115. https://doi.org/10.1016/j.vetmic.2004.05.009